Bronchiectasis

Bronchiectasis is a chronic lung condition marked by irreversible widening and scarring of the airways, often caused by repeated infections, autoimmune diseases, or genetic disorders like cystic fibrosis. This damage impairs mucus clearance, leading to persistent cough, excess sputum, and frequent respiratory infections. 

In 2025, treatment is increasingly personalized, focusing on managing symptoms, preventing exacerbations, and addressing underlying causes. A promising development is brensocatib, a drug targeting neutrophilic inflammation, which could significantly change the treatment landscape. Early diagnosis and multidisciplinary care are essential to improving quality of life and slowing disease progression.